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Viral fibers play a central role in many virus infection mechanisms since they recognize the corresponding host and establish a mechanical link to its surface. Specifically, bacteriophages have
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Here, we introduce RBPseg, a method that combines monomeric ESMFold predictions with a structural- based domain identification approach, to divide tail fiber sequences into
It is shown that adsorbability of T4 is regularly correlated with the extended state of the tail fibers, suggesting that in T4 fiber extension is a necessary condition for adsorption. Furthermore the
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To address this challenge, an overwhelming number of phages use a structure known as a tail. The tail creates a conduit between the phage capsid and host cytoplasm and allows the phage particle to
Here, the authors present structural and functional insight into the capsid, tail and tail fibres and how this impacts infectivity.
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In this paper we explore further the role of the whiskers in tail fiber attachment. We show that whiskers promote attachment, probably through the same interaction responsible for tail fiber
Using this approach, we generated complete tail fiber models, validated by single- particle cryo–electron microscopy of five fibers from three phages. A structural classification of 67 fibers
Tail fibers are responsible for the specific, albeit reversible primary attachment to host cell.
We contrast and compare the small genome, virulent, non-contractile tailed phages that infect the bacterial order Enterobacteriales. These phages, with genomes in the 35–60 kbp range,
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Together with the nucleic-acid containing capsid, a virus possesses other structures, such as the tails and the fibers, whose physical properties have not been studied yet with single molecule techniques
In this study, the team investigated the structural dynamics of the tail fibers of T7 bacteriophage. The T7 virion consists of an icosahedral capsid (*2) and a tail-fiber complex, which
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Similar to fiber optic jumpers, tail fibers are classified into single-mode and multimode types, differing in color, wavelength, and transmission distances. Generally, multimode tail fibers are
Squirrel tail fibers, especially from pine squirrels, offer buoyant, soft, and durable options for palmering and tailing bodies. This article surveys top squirrel tail tying materials available on
Here, we present the structure of DT57C determined by cryo-EM, and an atomic model of the virus, which was further explored using all-atom molecular dynamics simulations.
Using this approach, we generated complete tail fiber models, validated by single-particle cryo–electron microscopy of five fibers from three phages. A structural classification of 67 fibers
We show that during phage infection, this system specifically conjugates the ubiquitin-like protein to the phage central tail fibre, a protein at the
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